Puberty is associated with increased deterioration of renal function in patients with CKD: data from the ItalKid Project

Abstract

The present analysis suggests that puberty is associated with increased deterioration of renal function in CKD. The mechanism(s) underlying this unique and specific (to children) pattern of progression have not yet been identified, but it may be that sex hormones play a role in this puberty-related progression of CKD.