Prognostic Role of Serum Levels of Uric Acid in Amyotrophic Lateral Sclerosis

Abstract

ALS patients had lower serum UA levels than did healthy individuals. UA levels in ALS were negatively correlated with the rate of disease progression and positively associated with survival, suggesting that UA levels contribute to the progression of ALS. UA levels could be considered a biomarker of disease progression in the early phase in ALS patients.