Comparison of cefoxitin and moxalactam 30 µg disc diffusion methods for detection of methicillin resistance in coagulase-negative staphylococci

Abstract

Although all DD methods studied here performed well for detecting methicillin resistance in CoNS, moxalactam had a higher accuracy than cefoxitin to differentiate heteroresistant isolates from PBP2a-negative strains. Identification of isolates that should be submitted to a confirmatory test to conclude on methicillin resistance can be easily obtained by combining cefoxitin and moxalactam DD methods.