Regional cerebral blood flow by SPECT imaging in Sturge-Weber disease: an aid for diagnosis.

Catherine Chiron, C. Raynaud, N. Tzourio, C Diebler, Olivier Dulac, Mônica Zilbovicius, A. Syrota

Journal of Neurology Neurosurgery & Psychiatry · 1989 · 68 citations · 15 references

DOIFull text

Open access

Concepts

Abstract

Regional cerebral blood flow (rCBF) was studied using SPECT (single photon emission computed tomography) with 133-Xenon in 13 patients with confirmed Sturge-Weber disease, aged 9 months to 18 years. CT scan, performed at the same time, showed evident cerebral angioma in 10 but not in three. A marked hypoperfused area was found in all patients, ranging from -32% to -72% and of the same location as the CT signs. The hypoperfusion seems to result from post ictal phenomenon as well as from chronic ischaemia. SPECT imaging is therefore a sensitive method for visualising intracranial angioma in Sturge-Weber disease and it provides an aid for diagnosis when a CT scan is not reliable.

References

15