Monoclonal Antibodies to Vascular Endothelial Growth Factor (VEGF) And the VEGF Receptor, FLT-1, Inhibit the Growth of C6 Glioma in a Mouse Xenograft

Vascular Endothelial Growth Factor Is a Secreted Angiogenic Mitogen

David W. M. Leung, George Cachianes, Wun-Jing Kuang et al. · Science · 1989 · 5K citations

Life Sciences, Cell Biology, Molecular Biology +10

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

Dorit Shweiki, Ahuva Itin, Dov Soffer et al. · Nature · 1992 · 4.6K citations

Life Sciences, Physiology, Tissue Differentiation +11

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

K. Jin Kim, Bing Li, Jane Winer et al. · Nature · 1993 · 3.6K citations

Medicine, Cancer Biology, Oncology +14

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

Guo‐Hua Fong, Janet Rossant, Marina Gertsenstein et al. · Nature · 1995 · 2.6K citations

Life Sciences, Cell Biology, Molecular Biology +13

Vascular Permeability Factor, an Endothelial Cell Mitogen Related to PDGF

Pamela J. Keck, Scott D. Hauser, Gwen G. Krivi et al. · Science · 1989 · 2.1K citations

Life Sciences, Biochemistry, Molecular Biology +13