Über ein neues Glykosidierungsverfahren II. Glykoside des 4′‐Demethylepipodophyllotoxins. 23. Mitteilung über mitosehemmende Naturstoffe [1]

Abstract

Abstract 4′‐Demethylepipodophyllotoxin‐β‐ D ‐glucopyranoside (VIII) and 4′‐demethylepipodophyllotoxin‐β‐ D ‐galactopyranoside (X) have been synthesized by reaction of the aglycones III and IV with the corresponding tetra‐O‐acetyl‐β‐ D ‐hexopyranose in the presence of BF 3 ‐etherate. The suggested configurations at C‐1 of the aglycone moiety in the new glycosides could be confirmed by NMR.‐spectra.