Impaired wakefulness is associated with reduced anterior cingulate CBF in patients with normal pressure hydrocephalus

Abstract

IW in NPH is associated with reduced rrCBF in the anterior cingulate cortex. Improved wakefulness following surgery corresponds to rrCBF increments in the frontal association cortex. This study provides support for a functional coupling between frontal, hippocampal, thalamic and mesencephalic rrCBF in NPH at large.