Journal of Computational Chemistry · 2004 · 115 citations · 11 references
Life SciencesBioinformaticsGeneticsGene StructureGenomicsSequence AnalysisDna StructureGenomic Data VisualizationNucleic Acid StructureGraphical Data RepresentationGraphical ModelsGraphical Representation Of DataThree-dimensional Vector Modeling
We consider a 2D graphical representations of DNA sequences, which avoids loss of information associated with crossing and overlapping of the corresponding curve. We outline an approach, which is based on the construction of a three-component vector whose components are the normalized leading eigenvalues of the L/L matrices associated with DNA. The examination of similarities/dissimilarities among the coding sequences of the first exon of beta-globin gene of different species illustrates the utility of the approach.
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