arXiv (Cornell University) · 2012 · 23 citations · 13 references
ComputingComputer ScienceGene Expression AnalysisMachine LearningStatistical LearningDimension ReductionDimensionality ReductionFeature SelectionGene Expression ProfilingOptimization For Machine LearningRepresentation LearningGroup LassoLassoLinear Discriminant AnalysisSparse Linear AlgebraSparse Models
We present a novel approach to the formulation and the resolution of sparse Linear Discriminant Analysis (LDA). Our proposal, is based on penalized Optimal Scoring. It has an exact equivalence with penalized LDA, contrary to the multi-class approaches based on the regression of class indicator that have been proposed so far. Sparsity is obtained thanks to a group-Lasso penalty that selects the same features in all discriminant directions. Our experiments demonstrate that this approach generates extremely parsimonious models without compromising prediction performances. Besides prediction, the resulting sparse discriminant directions are also amenable to low-dimensional representations of data. Our algorithm is highly efficient for medium to large number of variables, and is thus particularly well suited to the analysis of gene expression data.
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THE USE OF MULTIPLE MEASUREMENTS IN TAXONOMIC PROBLEMS
Ronald Aylmer Fisher · Annals of Eugenics · 1936 · 14.7K citations · Full text
Penalized Discriminant Analysis
Trevor Hastie, Andreas Buja, Robert Tibshirani · The Annals of Statistics · 1995 · 864 citations · Full text