GENETIC DETERMINATION OF TYROSINASE THERMOSTABILITY IN NEUROSPORA

Abstract

was shown in a previous study that the tyrosinase activity of wild strain The strain produces almost no tyrosinase activity when cultured at 35" C on a medium which favors the production of strong activity in 25" cultures. The evidence indicated that the temperature effect is not due to formation of a tyrosinase inhibitor, but to a net decrease in tyrosinase synthesis at the higher temperature. Attention has been called to the resemblance between this case and that of the Himalayan rabbit, in which the formation of melanin, the end-product of tyrosinase activity, fails to take place at body temperature