Differential Lumbar Spinal Cord Responses among Wild Type, CD4 Knockout, and CD40 Knockout Mice in Spinal Nerve L5 Transection-Induced Neuropathic Pain

Abstract

Altogether, data indicate that both CD4 and CD40 play a role in L5Tx-induced leukocyte infiltration into the lumbar spinal cord but have differential contributions to spinal cord microglial activation following peripheral nerve injury.