Journal of Developmental & Behavioral Pediatrics · 2004 · 1.2K citations · 26 references
EducationHuman DevelopmentPediatricsChild DevelopmentDevelopmental PsychologyDevelopmental PsychopathologyAdverse Childhood ExperiencesAlcohol Use DisorderChildhood Risk FactorsFetal Alcohol Spectrum DisordersFetal OutcomesPrenatal DevelopmentAlcohol-related Neurodevelopmental DisorderFetal Alcohol ExposureFetal Alcohol Spectrum Disorders EpidemiologyLife History InterviewingMedian AgeProtective Factors Analysis
Fetal Alcohol Syndrome and Effects are linked to significant adaptive behavior challenges. The study examined 18 risk/protective factors and five adverse life outcomes in 415 FAS/FAE patients using Life History Interviews. Among these patients, 80 % were not raised by their biological mothers, and 61 % had disrupted schooling, 60 % legal trouble, 50 % confinement, 49 % repeated inappropriate sexual behaviors, and 35 % alcohol/drug problems; early diagnosis and stable rearing environments increased the odds of avoiding these outcomes by two- to fourfold.
Clinical descriptions of patients with Fetal Alcohol Syndrome (FAS) and Fetal Alcohol Effects (FAE) suggest major problems with adaptive behavior. Five operationally defined adverse outcomes and 18 associated risk/protective factors were examined using a Life History Interview with knowledgeable informants of 415 patients with FAS or FAE (median age 14 years, range 6-51; median IQ 86, range 29-126). Eighty percent of these patients were not raised by their biological mothers. For adolescents and adults, the life span prevalence was 61% for Disrupted School Experiences, 60% for Trouble with the Law, 50% for Confinement (in detention, jail, prison, or a psychiatric or alcohol/drug inpatient setting), 49% for Inappropriate Sexual Behaviors on repeated occasions, and 35% for Alcohol/Drug Problems. The odds of escaping these adverse life outcomes are increased 2- to 4-fold by receiving the diagnosis of FAS or FAE at an earlier age and by being reared in good stable environments.
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Richard A. Brown, Trevor Hastie, Robert Tibshirani · Biometrics · 1991 · 8.3K citations
RECOGNITION OF THE FETAL ALCOHOL SYNDROME IN EARLY INFANCY
KennethL. Jones, DavidW. Smith · The Lancet · 1973 · 2.8K citations
Medicine, Obstetrics, Pediatrics +10
PATTERN OF MALFORMATION IN OFFSPRING OF CHRONIC ALCOHOLIC MOTHERS
KennethL. Jones, DavidW. Smith, ChristyN. Ulleland et al. · The Lancet · 1973 · 2.2K citations
L Wickstrom, K Pettersson · PubMed · 1964 · 1.2K citations
Fetal alcohol syndrome: diagnosis, epidemiology, prevention, and treatment
Choice Reviews Online · 1997 · 921 citations
Medicine, Obstetrics, Pediatrics +17