MULTIPLE KERATOACANTHOMAS: REPORT OF FOUR CASES†

Abstract

Four cases illustrating aspects of multiple keratoacanthoma syndromes are reported. One patient with the classical picture of the familial Ferguson Smith variety provided an additional example of an affected family from Glasgow where the majority of the early cases were studied. The second patient displayed striking susceptibility to the effect of minor trauma in provoking new tumours and provided a unique model for the observation of the development of Keratoacanthoma. The third patient demonstrated complete disappearance of tumours during an episode of exfoliative dermatitis. The fourth patient provided an example of the interaction of nodular neurodermatitis and multiple keratoacanthomas.