Concepedia

Publication | Closed Access

Low-density lipoprotein receptor-related protein 1 mediates hypoxia-induced very low density lipoprotein-cholesteryl ester uptake and accumulation in cardiomyocytes

DOI

62

Citations

32

References

2012

Year

Roi Cal, José Castellano, Elena Revuelta‐López, Rosa Aledo, Montse Barriga, Jordi Farré, Gemma Vilahur, Laura Nasarre, Leif Hove‐Madsen, Lina Badimón,
Cardiovascular Research

Abstract

Our results demonstrate that hypoxia increases LRP1 expression through HIF-1α and that LRP1 overexpression mediates hypoxia-induced VLDL-CE uptake and accumulation in cardiomyocytes.

References

YearCitations

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