Graphene-DNA hybrids: self-assembly and electrochemical detection performance

Abstract

Graphene combines with single-stranded DNA by a self-assembly process under strong ultrasonication and in the resulting water-dispersible graphene-DNA hybrids, monolayers of globular ss-DNA molecules are adsorbed on both sides of the graphene sheets by a non-covalent π–π stacking. The cyclic voltammetry results of the graphene-DNA hybrids coated electrodes demonstrate a well-defined and nearly symmetrical redox characteristic which means an enhanced electron transfer on the electrode surface as compared to the uncoated glassy carbon electrodes. Accordingly, the coated ones show apparently better sensing performance towards hydrogen peroxide which is characterized by large detection range, rapid response and high sensitivity.