Concepedia

Effects of Glutathione and Ascorbic Acid on Streptomycin Sensitivity of <i>Escherichia coli</i>

Manish Goswami, Suhas H. Mangoli, Narendra Jawali

Antimicrobial Agents and Chemotherapy · 2007 · 56 citations · 20 references

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Abstract

We examined the effects of antioxidants and the role of reactive oxygen species (ROS) on the antibacterial action of aminoglycosides in Escherichia coli. We concluded that reduced streptomycin sensitivity in the presence of glutathione and ascorbic acid is not due to the antioxidant-mediated scavenging of ROS.

References

20

Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics

Andrew P. Carter, William Clemons, Ditlev E. Brodersen et al. · Nature · 2000 · 1.6K citations

, , +14

Alkyl Hydroperoxide Reductase Is the Primary Scavenger of Endogenous Hydrogen Peroxide in <i>Escherichia coli</i>

Lauren Costa Seaver, James A. Imlay · Journal of Bacteriology · 2001 · 794 citations · Full text

, , +17

Protein oxidation in response to increased transcriptional or translational errors

Sam Dukan, Anne Farewell, Manuel Ballesteros et al. · Proceedings of the National Academy of Sciences · 2000 · 331 citations

, , +17

Oxidative stress involved in the antibacterial action of different antibiotics

Inés Albesa, M. C. Becerra, Paola C. Battán et al. · Biochemical and Biophysical Research Communications · 2004 · 213 citations

, , +16

Involvement of Reactive Oxygen Species in the Action of Ciprofloxacin against<i>Escherichia coli</i>

M. Goswami, Suhas H. Mangoli, Narendra Jawali · Antimicrobial Agents and Chemotherapy · 2006 · 211 citations · Full text

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