Effects of Glutathione and Ascorbic Acid on Streptomycin Sensitivity of <i>Escherichia coli</i>

Abstract

We examined the effects of antioxidants and the role of reactive oxygen species (ROS) on the antibacterial action of aminoglycosides in Escherichia coli. We concluded that reduced streptomycin sensitivity in the presence of glutathione and ascorbic acid is not due to the antioxidant-mediated scavenging of ROS.