Endothelial Cell Glycocalyx Modulates Immobilization of Leukocytes at the Endothelial Surface

Abstract

Endothelial glycocalyx degradation stimulates leukocyte immobilization at the endothelial surface. Circulating heparan sulfate and heparin attach to the venule wall and attenuate Ox-LDL-induced leukocyte immobilization.