Copper‐Catalyzed Highly Regio‐ and Stereoselective Directed Hydroboration of Unsymmetrical Internal Alkynes: Controlling Regioselectivity by Choice of Catalytic Species

Abstract

Taking control of boron: A highly regio- and stereoselective copper-catalyzed hydroboration of unsymmetrical internal alkynes has been developed. The regioselectivity was successfully controlled by the choice of catalytic species (copper hydride or boryl copper; see scheme).