Signalosomes as therapeutic targets

PKA Phosphorylation Dissociates FKBP12.6 from the Calcium Release Channel (Ryanodine Receptor)

Steven O. Marx, Steven Reiken, Yuji Hisamatsu et al. · Cell · 2000 · 2K citations · Full text

Life Sciences, Biochemistry, Cell Biology +16

The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways

Kimberly L. Dodge‐Kafka, Joseph S. Soughayer, Geneviève C. Paré et al. · Nature · 2005 · 552 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

Nesprin-1 and -2 are involved in the pathogenesis of Emery–Dreifuss muscular dystrophy and are critical for nuclear envelope integrity

Qiuping Zhang, Cornelia Bethmann, Nathalie F. Worth et al. · Human Molecular Genetics · 2007 · 538 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module

Kimberly L. Dodge, Samone Khouangsathiene, Michael S. Kapiloff et al. · The EMBO Journal · 2001 · 502 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Proteomic, Functional, and Domain-Based Analysis of In Vivo 14-3-3 Binding Proteins Involved in Cytoskeletal Regulation and Cellular Organization

Jing Jin, F. Donelson Smith, Chris Stark et al. · Current Biology · 2004 · 446 citations · Full text

Life Sciences, Biochemistry, Cell Biology +16