Metrics and Textural Features of MRI Diffusion to Improve Classification of Pediatric Posterior Fossa Tumors

Abstract

Support vector machine-based classifiers using ADC histogram features yielded very good discrimination among pediatric posterior fossa tumor types, and ADC textural features show promise for further subtype discrimination. These findings suggest an added diagnostic value of quantitative feature analysis of diffusion MR imaging in pediatric neuro-oncology.