Journal of Bone and Joint Surgery - British Volume · 1996 · 149 citations · 6 references
MedicineOrthopaedic SurgeryOrthopedic SurgeryInflammationJoint Replacement SurgeryOrthopedicsAcute InflammationChronic InflammationHip ArthroplastyInflammatory ProcessesJoint DiseaseKnee ArthroplastyAcute-phase ProteinsC-reactive Protein TestingInflammation-related Protein ChangesPostoperative Medical ComplicationsSynovial BiomarkersSystemic Inflammation Markers
Any operation induces an elevation in the level of serum C-reactive protein (CRP). After hip and knee arthroplasty the maximal values are seen on the second and third postoperative days, after which the CRP decreases rapidly. There is no difference between patients with cemented or uncemented prostheses. Major postoperative complications may cause a further increase in CRP levels at one and two weeks.
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