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Transcriptional Regulation of CXCR4 in Prostate Cancer: Significance of TMPRSS2-ERG Fusions

DOIFull Paper Access

42

Citations

52

References

2013

Year

Rajareddy Singareddy, Louie Semaan, M. Katie Conley‐LaComb, Jason St. John, Katelyn Powell, Matthew K. Iyer, Daryn Smith, Lance K. Heilbrun, Dongping Shi, Wael Sakr,
Molecular Cancer Research

Abstract

These findings provide a mechanistic link between TMPRSS2-ERG translocations and intracellular kinase-mediated phosphorylation of ERG on enhanced metastasis of tumor cells via CXCR4 expression and function in prostate cancer cells.

References

YearCitations

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