Anti‐leucocyte antibodies in platelet apheresis donors with and without prior immunizing events: implications for <scp>TRALI</scp> prevention

Abstract

Platelet apheresis donors without history of immunization have anti-leucocyte antibodies that potentially can cause TRALI. In our opinion, this cohort should be included in screening strategies for TRALI prevention. As references and consensus cut-offs have not yet been established, it is premature to use microbead assays as standard for donor screening.