Effect of Membrane Cholesterol on BSEP/Bsep Activity: Species Specificity Studies for Substrates and Inhibitors

A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis

Sandra Strautnieks, Laura N. Bull, Alexander S. Knisely et al. · Nature Genetics · 1998 · 999 citations

Medicine, Genetics, Molecular Genetics +13

The Sister of P-glycoprotein Represents the Canalicular Bile Salt Export Pump of Mammalian Liver

Thomas Gerloff, Bruno Stieger, Bruno Hagenbuch et al. · Journal of Biological Chemistry · 1998 · 938 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Congenital Jaundice in Rats with a Mutation in a Multidrug Resistance-Associated Protein Gene

Coen C. Paulusma, Piter J. Bosma, Guido J.R. Zaman et al. · Science · 1996 · 832 citations

Medicine, Genetics, Molecular Genetics +17

Molecular Pathogenesis of Cholestasis

Michael Trauner, Peter J. Meier, James L. Boyer · New England Journal of Medicine · 1998 · 701 citations

Medicine, Biochemistry, Molecular Biology +17

Drug- and estrogen-induced cholestasis through inhibition of the hepatocellular bile salt export pump (Bsep) of rat liver

Bruno Stieger, Karin Fattinger, Jerzy Madon et al. · Gastroenterology · 2000 · 583 citations · Full text

Life Sciences, Biochemistry, Pharmacology +13