Functional Analysis of Insertion Sequence IS <i>Aba1</i> , Responsible for Genomic Plasticity of <i>Acinetobacter baumannii</i>

Abstract

ISAba1 is an insertion sequence that is widely distributed in Acinetobacter baumannii. We demonstrated here that ISAba1 and the composite transposon Tn2006 are capable of transposition, generating 9-bp target site duplications. The expression of the ISAba1 transposase-encoding gene was downregulated by translational frameshifting.