A Chiral‐Anion Generator: Application to Catalytic Desilylative Kinetic Resolution of Silyl‐Protected Secondary Alcohols

Abstract

Getting the grips on fluoride: Chiral hydroxy-terminated polyethers bearing a 3,3′-halogen-substituted chiral 1,1′-bi-2-naphthol (BINOL) unit manifest a new structural motif for chiral-anion generators. Their unique properties are revealed through highly enantioselective desilylative kinetic resolution of a variety of silyl-protected racemic alcohols with KF (see scheme). Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.