Donor transmission of Cryptococcus neoformans presenting late after renal transplantation

Abstract

We describe donor-transmitted Cryptococcus neoformans infection in a renal transplant recipient. The donor had no apparent risk factors for cryptococcal infection. The disease in the recipient, who did not receive prophylaxis, manifested relatively late at 50 days post-transplantation. We discuss the epidemiology and management of cryptococcal disease in solid organ transplant recipients and lessons learned from this case.