Expression of Membrane-Associated Mucins in Limbal Stem Cell Deficiency and after Transplantation of Cultivated Limbal Epithelium

Abstract

A tissue-specific expression of MUC1 and MUC4 but not MUC16 was found in human cornea and conjunctiva. LSCD led to a conjunctival expression pattern of mucins on the corneal surface. A corneal phenotype could be restored after TCLE, confirming the potential of this method to reconstruct the corneal surface.