Concepedia

ErmB Determinants and Tn <i>916</i> -Like Elements in Clinical Isolates of <i>Clostridium difficile</i>

Patrizia Spigaglia, Valentina Carucci, Fabrizio Barbanti, Paola Mastrantonio

Antimicrobial Agents and Chemotherapy · 2005 · 53 citations · 22 references

DOI

Concepts

Abstract

Erythromycin and tetracycline resistance was analyzed in 37 Clostridium difficile clinical isolates. Strains of different clonal origins showed different erythromycin and tetracycline resistance determinants and different genetic arrangements of the elements. In strains of recent isolation, the presence of Tn916-like elements, never found before in C. difficile clinical isolates, has been demonstrated.

References

22

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Tn5253, the pneumococcal omega (cat tet) BM6001 element, is a composite structure of two conjugative transposons, Tn5251 and Tn5252

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Genetic analysis of a tetracycline resistance element from Clostridium difficile and its conjugal transfer to and from Bacillus subtilis

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The conjugative transposon Tn925: enhancement of conjugal transfer by tetracycline in Enterococcus faecalis and mobilization of chromosomal genes in Bacillus subtilis and E. faecalis

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