Maximizing the ex vivo expansion of human mesenchymal stem cells using a microcarrier-based stirred culture system

Propagation and senescence of human marrow stromal cells in culture: a simple colony‐forming assay identifies samples with the greatest potential to propagate and differentiate

Carla M. DiGirolamo, David Stokes, David C. Colter et al. · British Journal of Haematology · 1999 · 876 citations · Full text

Tissue Engineering, Engineering, Adult Stem Cell +19

Human platelet lysate can replace fetal bovine serum for clinical‐scale expansion of functional mesenchymal stromal cells

Katharina Schallmoser, Christina Bartmann, Eva Rohde et al. · Transfusion · 2007 · 503 citations

In Vitro Expansion of Human Mesenchymal Stem Cells: Choice of Serum Is a Determinant of Cell Proliferation, Differentiation, Gene Expression, and Transcriptome Stability

Aboulghassem Shahdadfar, Katrine Frønsdal, Terje Haug et al. · Stem Cells · 2005 · 487 citations · Full text

Ex vivo expansion of human mesenchymal stem cells: A more effective cell proliferation kinetics and metabolism under hypoxia

Francisco dos Santos, Pedro Z. Andrade, Joana S. Boura et al. · Journal of Cellular Physiology · 2009 · 306 citations

Optimization of in vitro expansion of human multipotent mesenchymal stromal cells for cell‐therapy approaches: Further insights in the search for a fetal calf serum substitute

M.E. Bernardo, Maria Antonietta Avanzini, Cesare Perotti et al. · Journal of Cellular Physiology · 2006 · 276 citations