Publication | Open Access
Thalidomide as a Nitric Oxide Synthase Inhibitor and Its Structural Development
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Citations
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References
2004
Year
Medicinal ChemistryBioorganic ChemistryStructural DevelopmentBiochemistryReactive Nitrogen SpecieNatural SciencesMedicine-Inhibitory ActivityStructural Development StudiesMechanism Of ActionChemical BiologyPharmacologyPharmaceutical ChemistryNitrosative StressDrug Discovery
Thalidomide has been found to exhibit weak nitric oxide synthase (NOS)-inhibitory activity. Structural development studies of thalidomide showed that some N-2,6-dimethylphenylhomophthalimide analogs possess NOS-inhibiting activity.
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