Number and Function of Endothelial Progenitor Cells as a Marker of Severity for Diabetic Vasculopathy

Abstract

This study demonstrates that EPC decrease is related to PAD severity and that EPC function is altered in diabetic subjects with PAD, strengthening the pathogenetic role of EPC dysregulation in diabetic vasculopathy. EPC count may be considered a novel biological marker of peripheral atherosclerosis in diabetes.