Exhaustion of Racing Sperm in Nature‐Mimicking Microfluidic Channels During Sorting

Savaş Taşoğlu, Hooman Safaee, Xiao Hui Zhang, James L. Kingsley, Paolo N. Catalano, Umut A. Gürkan, Aida Nureddin, Emre Kayaalp, Raymond M. Anchan, Richard L. Maas,

Small · 2013 · 123 citations · 29 references

DOIFull text

Open access

Concepts

Abstract

Fertilization is central to the survival and propagation of a species, however, the precise mechanisms that regulate the sperm's journey to the egg are not well understood. In nature, the sperm has to swim through the cervical mucus, akin to a microfluidic channel. Inspired by this, a simple, cost-effective microfluidic channel is designed on the same scale. The experimental results are supported by a computational model incorporating the exhaustion time of sperm. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

References

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