Anesthetic Sevoflurane Reduces Levels of Hippocalcin and Postsynaptic Density Protein 95

Early Exposure to Common Anesthetic Agents Causes Widespread Neurodegeneration in the Developing Rat Brain and Persistent Learning Deficits

Vesna Jevtović‐Todorović, Richard E. Hartman, Yukitoshi Izumi et al. · Journal of Neuroscience · 2003 · 2K citations · Full text

Medicine, Anesthesiology, Neuroscience +17

Early Exposure to Anesthesia and Learning Disabilities in a Population-based Birth Cohort

Robert T. Wilder, Randall P. Flick, Juraj Šprung et al. · Anesthesiology · 2009 · 1.4K citations · Full text

Medicine, Anesthesiology, Pediatrics +15

Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein

Martine Migaud, Paul Charlesworth, Maureen Dempster et al. · Nature · 1998 · 1.2K citations

Life Sciences, Neurobiology, Neuroscience +16

Cognitive and Behavioral Outcomes After Early Exposure to Anesthesia and Surgery

Randall P. Flick, Slavica K. Katusic, Robert C. Colligan et al. · PEDIATRICS · 2011 · 899 citations · Full text

Medicine, Anesthesiology, Surgery +14

Isoflurane-induced Neuroapoptosis in the Neonatal Rhesus Macaque Brain

Ansgar M. Brambrink, Alex S. Evers, Michael S. Avidan et al. · Anesthesiology · 2010 · 595 citations

Life Sciences, Neurobiology, Neuroscience +12