Bioorganic & Medicinal Chemistry Letters · 1999 · 23 citations · 7 references
MedicineEndocrinologyPharmacologyBone MetabolismCell SignalingInflammationBone Density RegulationBone DevelopmentBone EndocrinologyBone HealthOsteoblast BiologyOsteoblast FunctionOsteoblast SuppressionOsteoblastic Lineage CellsOsteoclast-regulating Cytokines
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Increased Osteoclast Development After Estrogen Loss: Mediation by Interleukin-6
Robert L. Jilka, Giao Hangoc, Giuseppe Girasole et al. · Science · 1992 · 1.5K citations
Medicine, Endocrinology, Immunology +17
IL-6 is produced by osteoblasts and induces bone resorption.
Yoshiko Ishimi, Chisato Miyaura, Cheng Jin et al. · The Journal of Immunology · 1990 · 1.1K citations
Medicine, Endocrinology, Immunology +14
Interleukin‐6 deficient mice are protected from bone loss caused by estrogen depletion.
Valeria Poli, R. Balena, Elena Fattori et al. · The EMBO Journal · 1994 · 753 citations · Full text
Medicine, Endocrinology, Immunology +16