Chiral gold nanoparticle-based electrochemical sensor for enantioselective recognition of 3,4-dihydroxyphenylalanine

Abstract

The enantioselective recognition of 3,4-dihydroxyphenylalanine using penicillamine-modified gold nanoparticles has been investigated. Smaller gold nanoparticles with one enantiomeric ligand facilitate the redox reaction of only one enantiomer of 3,4-dihydroxyphenylalanine, with cross inversion for the gold nanoparticles with the other enantiomeric ligand.