Thalamo-Cortical Activation and Connectivity During Response Preparation in Adults With Persistent and Remitted ADHD

Abstract

Decreased thalamo-cortical activation during response preparation was present in adults diagnosed with ADHD in childhood regardless of symptom remission in adulthood, and may be partly driven by less functional coordination between the brainstem and thalamus. Greater functional integration of the thalamo-cortical network might parallel symptom recovery.