Journal of Medical Case Reports · 2014 · 15 citations · 9 references
Veterinary MedicineInfectious DiseasesMicrobiologyMedical MicrobiologyMicrobial PathogenesisSepsisAntimicrobial TherapyBacteremia ManagementClinical Recognition Of SepsisComplications Of SepsisSepsis ManagementSeptic ShockCritical Care Antimicrobial TherapyEmpiric Antibacterial TherapyEmpiric Antibiotic TherapyLactate AcidosisLactic AcidosisSepsis Empiric RegimensSepsis Empiric TherapySeptic Shock Management
INTRODUCTION: Aeromonas hydrophila sometimes causes bacteremia, which can be fatal in compromised patients, such as those with liver cirrhosis. We present a case of septic shock due to Aeromonas hydrophila bacteremia in a patient with liver cirrhosis, which was successfully treated with rapid resuscitation and critical care. CASE PRESENTATION: A 71-year-old Japanese man with liver cirrhosis was transported to our emergency center by ambulance after presenting with gait difficulties and fever. On arrival, he exhibited shock and severe lactic acidosis, which was suggestive of sepsis, and was immediately resuscitated and administered empiric antibiotic therapy. He also displayed catecholamine-resistant hypotension, which was successfully treated with critical care including supportive therapies, such as polymyxin B hemoperfusion and cytokine-absorbing hemofiltration. Aeromonas hydrophila was detected in his initial blood cultures. CONCLUSIONS: Aeromonas septicemia should be considered in patients with alcoholic liver cirrhosis who have profound shock. In addition to goal-directed therapy and the prompt administration of empiric antibiotic therapy, aggressive critical care involving multiple supportive therapies can save such patients.
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