The Impact of Catecholamines on Defibrillation Threshold in Patients with Implanted Cardioverter Defibrillators

Abstract

Elevation of plasma norepinephrine concentrations reduces the DFT, while elevations in epinephrine had no effect. Norepinephrine seems to reduce DFT regardless of beta-blocker therapy but epinephrine's effects are beta-blocker dependent.