Risk Factors for Neurotoxicity in Newborns With Severe Neonatal Hyperbilirubinemia

Abstract

Newborns without risk factors for neurotoxicity have a higher tolerance for hyperbilirubinemia than recognized in management guidelines. The risk for BE in hemolytic disease varies with etiology. The great variation in response to TSB indicates that biological factors other than TSB values are important in the pathogenesis of BE.