Iron oxide nanoparticles suppress the production of IL-1beta via the secretory lysosomal pathway in murine microglial cells - Concepedia

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Iron oxide nanoparticles suppress the production of IL-1beta via the secretory lysosomal pathway in murine microglial cells

DOI Full Paper Access

80

Citations

35

References

2013

Year

Hsin‐Ying Wu, Min‐Chun Chung, Chia‐Chi Wang, Chung‐Hsiung Huang, Hong‐Jen Liang, Tong‐Rong Jan

Particle and Fibre Toxicology

Abstract

Our results demonstrated a contrasting effect of IONPs on the production of IL-1β and TNF-α by LPS-stimulated microglia, in which the attenuation of IL-1β by IONPs was mediated by inhibiting the secretory lysosomal pathway of cytokine processing.

References

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