A study on the inhibition of dihydrofolate reductase (DHFR) from Escherichia coli by gold(<scp>i</scp>) phosphane compounds. X-ray crystal structures of (4,5-dichloro-1H-imidazolate-1-yl)-triphenylphosphane-gold(<scp>i</scp>) and (4,5-dicyano-1H-imidazolate-1-yl)-triphenylphosphane-gold(<scp>i</scp>)

Abstract

A study on the inhibition of dihydrofolate reductase (DHFR) by gold(<sc>i</sc>) compounds has been performed.