Prediction of Colorectal Neoplasia by Quantitative Methylation Analysis of <i>Estrogen Receptor</i> Gene in Nonneoplastic Epithelium from Patients with Ulcerative Colitis

Abstract

These results suggest that the analysis of ER gene methylation in nonneoplastic colorectal epithelium could have the potential to be a useful adjunct for identifying individuals with longstanding and extensive UC who are at increased risk of neoplasia and contribute to more effective cancer surveillance.