Concepedia

A phase II, randomized, blinded study of the farnesyltransferase inhibitor tipifarnib combined with letrozole in the treatment of advanced breast cancer after antiestrogen therapy

Stephen Johnston, Semiglazov Vf, George Manikhas, Dominique Spaëth, Gilles Romieu, David Dodwell, Andrew Wardley, Patrick Neven, Annick Bessems, Youn C. Park,

Breast Cancer Research and Treatment · 2007 · 62 citations · 25 references

DOI

Concepts

References

25

New Guidelines to Evaluate the Response to Treatment in Solid Tumors

Patrick Therasse, Susan G. Arbuck, Elizabeth A. Eisenhauer et al. · JNCI Journal of the National Cancer Institute · 2000 · 15.7K citations

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Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase

Tommaso Simoncini, Ali Hafezi‐Moghadam, Derek P. Brazil et al. · Nature · 2000 · 1.4K citations · Full text

, , +16

Mechanisms of Tamoxifen Resistance: Increased Estrogen Receptor-HER2/neu Cross-Talk in ER/HER2-Positive Breast Cancer

Jianzhong Shou, Suleiman Massarweh, C. K. Osborne et al. · JNCI Journal of the National Cancer Institute · 2004 · 1.2K citations · Full text

, , +17

Letrozole, a new oral aromatase inhibitor for advanced breast cancer: double-blind randomized trial showing a dose effect and improved efficacy and tolerability compared with megestrol acetate.

P Dombernowsky, I E Smith, Geoffrey Falkson et al. · Journal of Clinical Oncology · 1998 · 640 citations

, , +16

Molecular Changes in Tamoxifen-Resistant Breast Cancer: Relationship Between Estrogen Receptor, HER-2, and p38 Mitogen-Activated Protein Kinase

Maya Gutierrez, Simone Detre, Stephen Johnston et al. · Journal of Clinical Oncology · 2005 · 489 citations · Full text

, , +15