Concepedia

Sigma-1 (σ1) receptor deficiency reduces β-amyloid25–35-induced hippocampal neuronal cell death and cognitive deficits through suppressing phosphorylation of the NMDA receptor NR2B

Jun Yin, Sha Sha, Tingting Chen, Conghui Wang, Juan Hong, Pinghui Jie, Rong Zhou, Lin Li, Masahiro Sokabe, Ling Chen

Neuropharmacology · 2014 · 30 citations · 38 references

DOI

Concepts

References

38

Natural Oligomers of the Alzheimer Amyloid-β Protein Induce Reversible Synapse Loss by Modulating an NMDA-Type Glutamate Receptor-Dependent Signaling Pathway

Ganesh M. Shankar, Brenda L. Bloodgood, Matthew Townsend et al. · Journal of Neuroscience · 2007 · 1.6K citations · Full text

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Aβ Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease

Pascale N. Lacor, Maria C. Buniel, Paul W. Furlow et al. · Journal of Neuroscience · 2007 · 1.2K citations · Full text

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Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs.

Debra Burdick, Brian Soreghan, Min‐Sung Kwon et al. · Journal of Biological Chemistry · 1992 · 998 citations · Full text

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Soluble Oligomers of Amyloid β Protein Facilitate Hippocampal Long-Term Depression by Disrupting Neuronal Glutamate Uptake

Shaomin Li, Soyon Hong, Nina E. Shepardson et al. · Neuron · 2009 · 962 citations · Full text

, , +14

Regulation of adult neurogenesis by excitatory input and NMDA receptor activation in the dentate gyrus

BS McEwen, Elizabeth Gould · Journal of Neuroscience · 1995 · 743 citations · Full text

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