Accuracy and reproducibility of automated estradiol-17beta and progesterone assays using native serum samples: results obtained in the Belgian external assessment scheme

Abstract

Few automated methods succeed in having an excellent reproducibility for E(2) and progesterone. Given the high bias values it is suggested that, for performance testing, results be compared whenever possible with a reference method. The linear relationship as assessed by comparing results with those obtained by ID-GC/MS using samples from different donors was not assured for most methods.