Anion‐Induced Synthesis and Combinatorial Selection of Polypyrrolic Macrocycles

Abstract

Stimulating reactions: The anion-induced synthesis of a new class of 2,6-diamidopyridine–bipyrrole macrocyclic receptors that undergo combinatorial selection as a result of their interaction with anionic guests has been demonstrated (see picture of the interaction of bipyrrole fragments with a sulfate ion). The outcome of this stimulus-driven reaction bears analogy to recent macrocycle-forming strategies based on dynamic combinatorial processes. Supporting information for this article (general methods and materials, synthetic experimental details, representative Job plots, UV/Vis titrations, corresponding binding isotherms, and details of affinity constant determinations, as well as X-ray crystallographic information, including CIF files) is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2005/z502393_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.