Metal-free synthesis of cyano acrylates via cyanuric chloride-mediated three-component reactions involving a cascade consists of Knoevenagel condensation/cyano hydration/esterification

Abstract

The synthesis of cyano acrylates has been achieved <italic>via</italic> an organocatalytic domino Knoevenagel reaction, hydration and esterification under metal-free conditions without using any additional solvent.