Concepedia

Prolonged response to cyclosporin-A in hypoplastic refractory anemia and correlation with in vitro studies.

Lucio Catalano, Carmine Selleri, Catello Califano, Luigiana Luciano, M Volpicelli, Stefano Rocco, Gennaro Varriale, Patrizia Ricci, Bruno Rotoli

PubMed · 2000 · 27 citations · 24 references

Abstract

About one half of hypoplastic RA patients benefited from CSA treatment. A larger study could verify whether in vitro culture of hematopoietic progenitors in the presence of CSA can predict the clinical response and whether this treatment could prolong patients' survival.

References

24

Fas antigen expression on CD34+ human marrow cells is induced by interferon gamma and tumor necrosis factor alpha and potentiates cytokine-mediated hematopoietic suppression in vitro

Jaroslaw P. Maciejewski, Carmine Selleri, Sarah N. Anderson et al. · Blood · 1995 · 494 citations · Full text

Antithymocyte globulin for patients with myelodysplastic syndrome

Jeffrey J. Molldrem, Mary Caples, Dimitriοs Mavroudis et al. · British Journal of Haematology · 1997 · 276 citations

Increased expression of Fas antigen on bone marrow CD34<sup>+</sup> cells of patients with aplastic anaemia

Jaroslaw P. Maciejewski, Carmine Selleri, T Sato et al. · British Journal of Haematology · 1995 · 255 citations

Interferon‐γ and tumor necrosis factor‐α suppress both early and late stages of hematopoiesis and induce programmed cell death

Carmine Selleri, T Sato, Stacie M. Anderson et al. · Journal of Cellular Physiology · 1995 · 232 citations

Cyclosporin A therapy in hypoplastic MDS patients and certain refractory anaemias without hypoplastic bone marrow

Anna Jonášová, R Neuwírtová, Jaroslav Čermák et al. · British Journal of Haematology · 1998 · 212 citations