Concepedia

Publication | Open Access

Melanoma Therapy via Peptide-Targeted α-Radiation

DOIFull Paper Access

133

Citations

27

References

2005

Year

Yubin Miao, Mark D. Hylarides, Darrell R. Fisher, Tiffani Shelton, Herbert Moore, D. W. Wester, Alan R. Fritzberg, Christopher T. Winkelmann, Timothy J. Hoffman, Thomas P. Quinn
Clinical Cancer Research

Abstract

Treatment of B16/F1 murine melanoma-bearing mice with (212)Pb[DOTA]-Re(Arg(11))CCMSH significantly decreased tumor growth rates resulting in extended mean survival times, and in many cases, complete remission of disease. (212)Pb-DOTA-Re(Arg(11))CCMSH seems to be a very promising radiopharmaceutical for targeted radionuclide therapy of melanoma.

References

YearCitations

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